TSEN2

Across TCGA patient cohorts, TSEN2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,151 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TSEN2-associated genes across cancer lineages are CHCHD4, CCDC138, and CLEC7A. Each is linked with TSEN2 in more than 3 cancer types. Because this analysis shows association rather than direction, both TSEN2-to-partner and partner-to-TSEN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TSEN2 versus CHCHD4 in LSCC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSEN2→partner) and Y-score (partner→TSEN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CHCHD4 →	+0.580	+0.419	<.001	<.001	3	4
LSCC	CCDC138 →	+0.507	+0.328	.003	<.001	3	3
OV	CLEC7A →	-1.007	-0.788	.005	.002	3	3
BRCA	NOP56 →	+0.508	+0.426	.001	.001	3	3
BRCA	RPL32 →	+0.375	+0.300	<.001	<.001	3	3
LSCC	LSM3 →	+0.428	+0.276	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,151 associations by consensus.

TSEN2 vs CHCHD4 — LSCC

Explore this scatter interactively →