TSEN15P2

Across TCGA pan-cancer cohorts, TSEN15P2 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of TSEN15P2’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where TSEN15P2 RNA is repressed in tumor relative to normal tissue. In most cancer types TSEN15P2 is over-expressed in tumor, although a few such as LUAD and BRCA show the opposite, repressed pattern.

LUAD, BRCA, and KIRP are the cancer types where TSEN15P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TSEN15P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	IV	−0.355	<.001	2	view →
BRCA	All	III,IV	−0.176	.011	2	view →
KIRP	All	III,IV	−0.100	.032	2	view →
LUSC	Female	III,IV	+0.580	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

TSEN15P2–LUAD

Open the LUAD breakdown →