TSC22D4

Across TCGA patient cohorts, TSC22D4 mutation is significantly associated with the RNA expression of many other genes, with 794 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TSC22D4-associated genes across cancer lineages are LINC02103, RPS28P1, and MIR8053. Each is linked with TSC22D4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSC22D4-to-partner and partner-to-TSC22D4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02103 grouped by TSC22D4-low versus TSC22D4-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSC22D4→partner) and Y-score (partner→TSC22D4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LINC02103 →	+0.282	+4.798	<.001	.006	3	2
LUAD	RPS28P1 →	+0.172	+5.197	<.001	.003	3	2
LUAD	MIR8053 →	+0.670	+5.928	<.001	<.001	3	2
UCEC	RNA5SP146 →	+0.410	+2.788	<.001	<.001	3	2
HNSC	CDY8P →	+0.019	+7.954	<.001	.008	3	1
UCEC	CENPM →	+0.689	+3.584	.003	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 794 associations by consensus.

LINC02103 by TSC22D4 expression — LUAD

Explore this box plot interactively →