TSC22D3

Across TCGA patient cohorts, TSC22D3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,857 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TSC22D3-associated proteins across cancer lineages are NR3C1_S45, ILK, and LRPPRC. Each is linked with TSC22D3 in more than 5 cancer types. Because this analysis shows association rather than direction, both TSC22D3-to-partner and partner-to-TSC22D3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TSC22D3 versus NR3C1_S45 in CCRCC, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TSC22D3→partner) and Y-score (partner→TSC22D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	NR3C1_S45 →	+0.773	+1.383	<.001	<.001	3	6
BRCA	ILK →	+0.369	+0.722	<.001	<.001	3	6
OV	LRPPRC →	-0.389	-0.817	.001	.009	3	6
LUAD	SEPTIN4 →	+0.466	+1.230	<.001	<.001	3	6
BRCA	KANK2 →	+0.454	+0.869	<.001	<.001	3	6
CCRCC	NR3C1_S211 →	+1.075	+2.063	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,857 associations by consensus.

TSC22D3 vs NR3C1_S45 — CCRCC

Explore this scatter interactively →