TSC22D3

Across TCGA patient cohorts, TSC22D3 protein abundance is significantly associated with the RNA expression of many other genes, with 13,998 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TSC22D3-associated genes across cancer lineages are NCBP2L, PFN1, and ZBTB16. Each is linked with TSC22D3 in more than 5 cancer types. Because this analysis shows association rather than direction, both TSC22D3-to-partner and partner-to-TSC22D3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TSC22D3 versus NCBP2L in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSC22D3→partner) and Y-score (partner→TSC22D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NCBP2L →	+0.535	+0.624	<.001	<.001	3	6
UCEC	PFN1 →	-0.518	-0.437	<.001	<.001	3	5
CCRCC	ZBTB16 →	+1.320	+0.267	.001	<.001	3	5
OV	EFCC1 →	+1.063	+0.553	<.001	<.001	3	5
UCEC	SPARCL1 →	+1.358	+0.426	<.001	<.001	3	5
OV	C1QTNF7 →	+0.729	+0.346	.006	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,998 associations by consensus.

TSC22D3 vs NCBP2L — BRCA

Explore this scatter interactively →