TSC22D3

Across TCGA cell cohorts, TSC22D3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,550 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TSC22D3-associated GO terms across cancer lineages are Regulation of activation-induced cell death of T cells, Response to steroid hormone, and Response to endoplasmic reticulum stress. Each is linked with TSC22D3 in more than 17 cancer types. Because this analysis shows association rather than direction, both TSC22D3-to-partner and partner-to-TSC22D3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of activation-induced cell death of T cells grouped by TSC22D3-low versus TSC22D3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSC22D3→partner) and Y-score (partner→TSC22D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of activation-induced cell death of T cells →	+0.529	+1.386	<.001	<.001	3	18
LUNG_NSCLC_LUSC	Response to steroid hormone →	+0.106	+1.848	<.001	.001	3	13
BONE	Response to endoplasmic reticulum stress →	+0.079	+1.696	<.001	<.001	3	13
URINARY_TRACT	Regulation of response to endoplasmic reticulum stress →	+0.077	+1.913	<.001	.002	3	12
LUNG_NSCLC_LUAD	Regulation of intrinsic apoptotic signaling pathway →	+0.067	+1.932	<.001	<.001	3	12
LUNG_NSCLC_LUAD	Regulation of lymphocyte apoptotic process →	+0.095	+1.693	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,550 associations by consensus.

Regulation of activation-induced cell death of T cells by TSC22D3 expression — LUNG_SCLC

Explore this box plot interactively →