Across TCGA patient cohorts, TSC22D2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,807 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TSC22D2-associated proteins across cancer lineages are NRBP1, HID1, and CRTAP. Each is linked with TSC22D2 in more than 4 cancer types. Because this analysis shows association rather than direction, both TSC22D2-to-partner and partner-to-TSC22D2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TSC22D2→partner) and Y-score (partner→TSC22D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NRBP1 →	+0.290	+0.650	<.001	<.001	3	5
PDAC	HID1 →	-0.490	-0.389	<.001	<.001	3	5
OV	CRTAP →	+0.465	+0.555	.001	.003	3	5
UCEC	ARHGAP26 →	-0.474	-0.694	<.001	<.001	3	4
GBM	RPS27L →	-0.518	-0.341	<.001	<.001	3	4
GBM	SEC23IP →	-0.279	-0.407	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,807 associations by consensus.

Exploration

TSC22D2 survival (RNA) · tumor vs normal (RNA) · all TSC22D2 data types