Across TCGA patient cohorts, TSC22D2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,913 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TSC22D2-associated genes across cancer lineages are EHD1, CRABP2, and DUSP7. Each is linked with TSC22D2 in more than 3 cancer types. Because this analysis shows association rather than direction, both TSC22D2-to-partner and partner-to-TSC22D2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSC22D2→partner) and Y-score (partner→TSC22D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	EHD1 →	+0.596	+0.281	.001	.002	3	4
LSCC	CRABP2 →	+1.561	+0.305	<.001	.001	3	4
HNSC	DUSP7 →	+0.537	+0.225	.001	.009	3	4
LUAD	FBXO45 →	+0.429	+0.309	<.001	<.001	3	4
HNSC	TMEM45A →	+1.129	+0.423	<.001	<.001	3	4
UCEC	DACT3 →	+0.755	+0.308	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,913 associations by consensus.

Exploration

TSC22D2 survival (RNA) · tumor vs normal (RNA) · all TSC22D2 data types