TSC1

Across TCGA cell cohorts, TSC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,501 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TSC1-associated GO terms across cancer lineages are Nucleic acid transport, RNA transport, and mRNA transport. Each is linked with TSC1 in more than 19 cancer types. Because this analysis shows association rather than direction, both TSC1-to-partner and partner-to-TSC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleic acid transport grouped by TSC1-low versus TSC1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSC1→partner) and Y-score (partner→TSC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nucleic acid transport →	+0.126	+0.962	<.001	<.001	3	19
BONE	RNA transport →	+0.126	+0.962	<.001	<.001	3	19
OESOPHAGUS	mRNA transport →	+0.118	+0.784	.003	.002	2	20
BONE	Establishment of RNA localization →	+0.112	+0.794	<.001	<.001	3	19
STOMACH	RNA export from nucleus →	+0.130	+0.960	<.001	<.001	3	18
STOMACH	RNA localization →	+0.104	+0.914	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,501 associations by consensus.

Nucleic acid transport by TSC1 expression — BONE

Explore this box plot interactively →