TRUB2

Across TCGA pan-cancer cohorts, TRUB2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TRUB2 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher TRUB2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TRUB2 expression acts as an unfavorable survival marker, although some lineages such as LSCC and HNSC show a favorable association.

LSCC, HNSC, and OV are the cancer types where TRUB2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Quartile	II,III,IV	0.866	0.367	.005	29	view →
HNSC	DFS	Median	All	0.860	0.341	.018	8	view →
OV	DFS	Median	All	1.000	0.706	.043	4	view →
CCRCC	OS	Median	III,IV	0.485	1.000	.036	3	view →
LUAD	DFS	Quartile	All	0.426	0.898	.025	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TRUB2–LSCC (DFS)

Open the LSCC breakdown →