TRUB2

Across TCGA patient cohorts, TRUB2 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRUB2-associated genes across cancer lineages are CD4+ Tem, Fibroblasts, and HSC. Each is linked with TRUB2 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRUB2-to-partner and partner-to-TRUB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tem grouped by TRUB2-low versus TRUB2-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRUB2→partner) and Y-score (partner→TRUB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	CD4+ Tem →	+0.024	+5.593	<.001	.040	3	3
UCEC	Fibroblasts →	+0.032	+2.715	.013	.006	3	1
UCEC	HSC →	+0.175	+3.010	.005	.020	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD4+ Tem by TRUB2 expression — PRAD

Explore this box plot interactively →