TRUB2

Across TCGA cell cohorts, TRUB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,604 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TRUB2-associated GO terms across cancer lineages are Mitochondrial tRNA pseudouridine synthesis, Positive regulation of mRNA 3'-end processing, and Nucleosome disassembly. Each is linked with TRUB2 in more than 14 cancer types. Because this analysis shows association rather than direction, both TRUB2-to-partner and partner-to-TRUB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial tRNA pseudouridine synthesis grouped by TRUB2-low versus TRUB2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRUB2→partner) and Y-score (partner→TRUB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Mitochondrial tRNA pseudouridine synthesis →	+0.160	+0.605	<.001	<.001	3	15
BONE	Positive regulation of mRNA 3'-end processing →	+0.107	+0.716	.004	.007	3	14
BLOOD_Lymphoma	Nucleosome disassembly →	+0.136	+0.781	<.001	<.001	3	13
URINARY_TRACT	CTP salvage →	+0.184	+0.883	<.001	<.001	3	13
BONE	RNA export from nucleus →	+0.096	+0.558	<.001	<.001	3	13
BLOOD_Myeloma	rRNA 5'-end processing →	+0.132	+1.041	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,604 associations by consensus.

Mitochondrial tRNA pseudouridine synthesis by TRUB2 expression — OVARY

Explore this box plot interactively →