Across TCGA cell cohorts, TRRAP mutation is significantly associated with the RNA expression of many other genes, with 2,082 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TRRAP-associated genes across cancer lineages are BCL7A, AZIN2, and SLC37A3. Each is linked with TRRAP in more than 3 cancer types. Because this analysis shows association rather than direction, both TRRAP-to-partner and partner-to-TRRAP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRRAP→partner) and Y-score (partner→TRRAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BCL7A →	+0.684	+2.115	.001	.004	3	4
URINARY_TRACT	AZIN2 →	+1.030	+3.321	.002	.002	2	4
BLOOD_Leukemia	SLC37A3 →	+1.226	+3.489	.003	.001	3	3
LARGE_INTESTINE	WRN →	+0.870	+3.782	<.001	<.001	3	3
LUNG_NSCLC_LUAD	GLO1 →	+0.475	+2.258	.006	.002	3	3
LUNG_NSCLC_LUAD	HACL1 →	+0.592	+2.584	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,082 associations by consensus.

Exploration

TRRAP survival (RNA) · tumor vs normal (RNA) · all TRRAP data types