TRPV5

Across TCGA patient cohorts, TRPV5 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,698 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRPV5-associated proteins across cancer lineages are RNF216_S719, SGTB, and SGTB_S77. Each is linked with TRPV5 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRPV5-to-partner and partner-to-TRPV5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRPV5 versus RNF216_S719 in PDAC, with a Pearson correlation of -0.23.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPV5→partner) and Y-score (partner→TRPV5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RNF216_S719 →	-0.487	-0.122	.003	<.001	3	3
GBM	SGTB →	+0.323	+0.604	.001	<.001	3	3
GBM	SGTB_S77 →	+0.596	+0.560	.002	<.001	3	3
COAD	ITGAX →	+0.483	+0.065	<.001	<.001	3	3
LUAD	LILRB4 →	+0.525	+0.106	<.001	.001	3	3
COAD	APOE →	+0.683	+0.050	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,698 associations by consensus.

TRPV5 vs RNF216_S719 — PDAC

Explore this scatter interactively →