TRPV5

Across TCGA patient cohorts, TRPV5 protein abundance is significantly associated with the RNA expression of many other genes, with 6,316 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TRPV5-associated genes across cancer lineages are TRAF1, C9orf139, and FUT7. Each is linked with TRPV5 in more than 4 cancer types. Because this analysis shows association rather than direction, both TRPV5-to-partner and partner-to-TRPV5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRPV5 versus TRAF1 in LUAD, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPV5→partner) and Y-score (partner→TRPV5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TRAF1 →	+0.826	+0.576	<.001	<.001	3	5
LSCC	C9orf139 →	+0.652	+0.840	<.001	<.001	3	4
LSCC	FUT7 →	+0.766	+0.750	<.001	<.001	3	4
LUAD	TRAJ43 →	+1.433	+0.355	<.001	.004	3	4
LUAD	MIR3142HG →	+1.140	+0.470	.002	.002	3	4
LSCC	FOXP3 →	+1.064	+0.615	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,316 associations by consensus.

TRPV5 vs TRAF1 — LUAD

Explore this scatter interactively →