Across TCGA patient cohorts, TRPV2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,767 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TRPV2-associated genes across cancer lineages are TLR8, IL21R, and CD86. Each is linked with TRPV2 in more than 8 cancer types. Because this analysis shows association rather than direction, both TRPV2-to-partner and partner-to-TRPV2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPV2→partner) and Y-score (partner→TRPV2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TLR8 →	+0.990	+0.412	<.001	<.001	3	9
HNSC	IL21R →	+1.001	+0.443	<.001	<.001	3	9
GBM	CD86 →	+0.953	+0.417	<.001	<.001	3	9
HNSC	SRGN →	+0.989	+0.386	<.001	<.001	3	9
OV	LILRB2 →	+1.147	+0.454	<.001	<.001	3	9
COAD	STX11 →	+0.738	+0.434	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,767 associations by consensus.

Exploration

TRPV2 survival (RNA) · tumor vs normal (RNA) · all TRPV2 data types