Across TCGA patient cohorts, TRPV2 mutation is significantly associated with the RNA expression of many other genes, with 3,946 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRPV2-associated genes across cancer lineages are MRPL49, C3orf33, and JKAMP. Each is linked with TRPV2 in more than 3 cancer types. Because this analysis shows association rather than direction, both TRPV2-to-partner and partner-to-TRPV2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPV2→partner) and Y-score (partner→TRPV2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MRPL49 →	+0.489	+3.321	<.001	<.001	3	4
UCEC	C3orf33 →	+0.391	+2.556	.001	<.001	3	4
UCEC	JKAMP →	+0.478	+1.736	<.001	<.001	3	4
UCEC	PPP2R5C →	+0.325	+2.000	<.001	<.001	3	4
UCEC	BLOC1S2 →	+0.408	+2.470	<.001	<.001	3	4
UCEC	CNIH1 →	+0.523	+1.736	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,946 associations by consensus.

Exploration

TRPV2 survival (RNA) · tumor vs normal (RNA) · all TRPV2 data types