Across TCGA cell cohorts, TRPV2 mutation is significantly associated with the RNA expression of many other genes, with 369 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRPV2-associated genes across cancer lineages are SLC35G3, MSGN1, and OR2D3. Each is linked with TRPV2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRPV2-to-partner and partner-to-TRPV2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPV2→partner) and Y-score (partner→TRPV2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SLC35G3 →	+0.036	+3.289	<.001	<.001	3	2
STOMACH	MSGN1 →	+0.115	+4.285	<.001	.007	3	1
STOMACH	OR2D3 →	+0.023	+4.432	<.001	.003	3	1
BLOOD_Leukemia	BRD1 →	+0.521	+3.199	.009	.007	3	1
BLOOD_Leukemia	ZBED4 →	+0.711	+3.199	.003	.007	3	1
BLOOD_Leukemia	R3HDML →	+0.008	+3.569	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 369 associations by consensus.

Exploration

TRPV2 survival (RNA) · tumor vs normal (RNA) · all TRPV2 data types