Across TCGA cell cohorts, TRPV1 mutation is significantly associated with the RNA expression of many other genes, with 186 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TRPV1-associated genes across cancer lineages are GPR101, OR56A1, and OR56A5. Each is linked with TRPV1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRPV1-to-partner and partner-to-TRPV1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPV1→partner) and Y-score (partner→TRPV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	GPR101 →	+0.106	+4.736	<.001	.009	3	2
UPPER_AERODIGESTIVE_TRACT	OR56A1 →	+0.059	+4.736	<.001	.009	3	2
UPPER_AERODIGESTIVE_TRACT	OR56A5 →	+0.027	+4.736	.001	.009	3	2
URINARY_TRACT	OR2A2 →	+0.046	+5.087	<.001	.004	3	1
BLOOD_Lymphoma	CABP5 →	+0.016	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	CST9 →	+0.060	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 186 associations by consensus.

Exploration

TRPV1 survival (RNA) · tumor vs normal (RNA) · all TRPV1 data types