TRPS1

Across TCGA pan-cancer cohorts, TRPS1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TRPS1 data layer compared with 21 for mass-spec protein and 11 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher TRPS1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TRPS1 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

PDAC, HNSC, and LUAD are the cancer types where TRPS1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	All	0.429	0.700	<.001	83	view →
HNSC	DFS	Quartile	III,IV	0.441	0.798	.005	28	view →
LUAD	DFS	Median	II,III,IV	0.751	0.940	.017	7	view →
CCRCC	DFS	Median	III,IV	0.434	1.000	.033	6	view →
LSCC	DFS	Median	All	0.972	0.898	.031	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TRPS1–PDAC (OS)

Open the PDAC breakdown →