TRPM2

Across TCGA cell cohorts, TRPM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,078 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRPM2-associated GO terms across cancer lineages are Dendritic cell chemotaxis, Amacrine cell differentiation, and Dendritic cell migration. Each is linked with TRPM2 in more than 11 cancer types. Because this analysis shows association rather than direction, both TRPM2-to-partner and partner-to-TRPM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dendritic cell chemotaxis grouped by TRPM2-low versus TRPM2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPM2→partner) and Y-score (partner→TRPM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Dendritic cell chemotaxis →	-0.213	-1.455	.001	.002	3	12
KIDNEY	Amacrine cell differentiation →	-0.116	-1.471	.001	<.001	3	7
SOFT_TISSUE	Dendritic cell migration →	-0.231	-1.917	.001	.001	2	7
LUNG_NSCLC_LUAD	Negative regulation of amine metabolic process →	-0.162	-1.802	.003	<.001	3	6
KIDNEY	Primary alcohol metabolic process →	-0.144	-2.174	<.001	<.001	3	6
BLOOD_Leukemia	Bile acid signaling pathway →	-0.183	-2.297	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,078 associations by consensus.

Dendritic cell chemotaxis by TRPM2 expression — SOFT_TISSUE

Explore this box plot interactively →