TRPM1

Across TCGA cell cohorts, TRPM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,141 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TRPM1-associated GO terms across cancer lineages are Regulation of synapse pruning, Endosomal vesicle fusion, and Retina homeostasis. Each is linked with TRPM1 in more than 4 cancer types. Because this analysis shows association rather than direction, both TRPM1-to-partner and partner-to-TRPM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of synapse pruning grouped by TRPM1-low versus TRPM1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPM1→partner) and Y-score (partner→TRPM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of synapse pruning →	-0.118	-0.047	.001	.003	3	5
SKIN	Endosomal vesicle fusion →	+0.054	+2.739	.002	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	Retina homeostasis →	-0.053	-0.048	<.001	.009	3	4
BLOOD_Leukemia	Regulation of cell proliferation in midbrain →	-0.824	-0.083	<.001	.004	3	4
SKIN	Response to insulin →	+0.029	+3.551	<.001	<.001	3	4
OVARY	Regulation of cell cycle G1/S phase transition →	+0.046	+0.119	.003	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,141 associations by consensus.

Regulation of synapse pruning by TRPM1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →