TRPC2

Across TCGA patient cohorts, TRPC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,605 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TRPC2-associated proteins across cancer lineages are ARHGAP18, TRPV2, and FBP2. Each is linked with TRPC2 in more than 4 cancer types. Because this analysis shows association rather than direction, both TRPC2-to-partner and partner-to-TRPC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRPC2 versus ARHGAP18 in GBM, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPC2→partner) and Y-score (partner→TRPC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ARHGAP18 →	+0.535	+0.278	<.001	<.001	3	5
UCEC	TRPV2 →	+0.566	+0.438	.001	.004	3	5
GBM	FBP2 →	+0.672	+0.184	<.001	<.001	3	5
COAD	MSR1_S27 →	+0.851	+0.121	<.001	<.001	3	5
LSCC	RNASE6 →	+0.511	+0.121	<.001	<.001	3	4
GBM	SNX2 →	+0.197	+0.237	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,605 associations by consensus.

TRPC2 vs ARHGAP18 — GBM

Explore this scatter interactively →