TRPC1

Across TCGA cell cohorts, TRPC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,721 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TRPC1-associated GO terms across cancer lineages are Peptidyl-lysine oxidation, Regulation of post-translational protein modification, and Regulation of intracellular transport. Each is linked with TRPC1 in more than 13 cancer types. Because this analysis shows association rather than direction, both TRPC1-to-partner and partner-to-TRPC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine oxidation grouped by TRPC1-low versus TRPC1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPC1→partner) and Y-score (partner→TRPC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Peptidyl-lysine oxidation →	+1.422	+1.677	<.001	<.001	3	14
STOMACH	Regulation of post-translational protein modification →	+0.079	+2.061	<.001	<.001	3	13
BONE	Regulation of intracellular transport →	+0.064	+1.723	<.001	<.001	3	13
BONE	Positive regulation of cell-substrate junction organization →	+0.154	+1.253	<.001	<.001	3	13
BONE	Positive regulation of focal adhesion assembly →	+0.246	+1.522	<.001	<.001	3	13
STOMACH	Response to molecule of fungal origin →	-1.528	-1.452	<.001	.003	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,721 associations by consensus.

Peptidyl-lysine oxidation by TRPC1 expression — BREAST

Explore this box plot interactively →