TRPA1

Across TCGA cell cohorts, TRPA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,901 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TRPA1-associated GO terms across cancer lineages are Response to carbon dioxide, Endosomal transport, and Positive regulation of protein localization to mitochondrion. Each is linked with TRPA1 in more than 13 cancer types. Because this analysis shows association rather than direction, both TRPA1-to-partner and partner-to-TRPA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to carbon dioxide grouped by TRPA1-low versus TRPA1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPA1→partner) and Y-score (partner→TRPA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Response to carbon dioxide →	+0.633	+1.366	.002	.001	3	14
SKIN	Endosomal transport →	+0.065	+0.960	<.001	<.001	3	10
LIVER	Positive regulation of protein localization to mitochondrion →	+0.116	+2.001	<.001	<.001	3	9
SKIN	Viral gene expression →	+0.094	+0.963	<.001	<.001	3	9
BLOOD_Lymphoma	Late endosome to vacuole transport via multivesicular body sorting pathway →	+0.068	+0.585	<.001	<.001	3	9
SKIN	Retrograde transport, endosome to Golgi →	+0.082	+0.976	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,901 associations by consensus.

Response to carbon dioxide by TRPA1 expression — URINARY_TRACT

Explore this box plot interactively →