TROAP

Across TCGA cell cohorts, TROAP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,976 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TROAP-associated GO terms across cancer lineages are Positive regulation of chromosome separation, Mitotic spindle elongation, and Mitotic spindle midzone assembly. Each is linked with TROAP in more than 19 cancer types. Because this analysis shows association rather than direction, both TROAP-to-partner and partner-to-TROAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of chromosome separation grouped by TROAP-low versus TROAP-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TROAP→partner) and Y-score (partner→TROAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of chromosome separation →	+0.206	+1.418	<.001	<.001	3	19
URINARY_TRACT	Mitotic spindle elongation →	+0.287	+1.398	<.001	<.001	3	19
URINARY_TRACT	Mitotic spindle midzone assembly →	+0.287	+1.398	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Meiotic cell cycle →	+0.099	+1.470	<.001	<.001	3	19
STOMACH	Mitotic metaphase chromosome alignment →	+0.141	+1.296	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	DNA replication checkpoint signaling →	+0.203	+1.580	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,976 associations by consensus.

Positive regulation of chromosome separation by TROAP expression — URINARY_TRACT

Explore this box plot interactively →