TRO

Across TCGA patient cohorts, TRO protein abundance is significantly associated with the protein abundance of many other proteins, with 1,801 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRO-associated proteins across cancer lineages are RANBP2_S2668, UNC93B1, and WDR5. Each is linked with TRO in more than 1 cancer types. Because this analysis shows association rather than direction, both TRO-to-partner and partner-to-TRO results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRO versus RANBP2_S2668 in BRCA, with a Pearson correlation of -0.61.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRO→partner) and Y-score (partner→TRO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RANBP2_S2668 →	-0.513	-1.063	.004	.001	3	2
LSCC	UNC93B1 →	-0.452	-0.716	<.001	.002	3	1
LSCC	WDR5 →	+0.344	+0.697	.001	.003	3	1
LSCC	YTHDC1 →	+0.388	+0.838	.002	<.001	3	1
LSCC	ZC3H18_S868 →	+0.461	+0.993	.001	.001	3	1
LSCC	ZGPAT →	+0.461	+0.905	<.001	<.001	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,801 associations by consensus.

TRO vs RANBP2_S2668 — BRCA

Explore this scatter interactively →