TRNT1

Across TCGA pan-cancer cohorts, TRNT1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TRNT1 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TRNT1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRNT1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and CCRCC show a favorable association.

UCEC, HNSC, and LSCC are the cancer types where TRNT1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	II,III,IV	0.269	0.928	.002	36	view →
HNSC	OS	Quartile	All	0.520	0.832	<.001	26	view →
LSCC	DFS	Median	All	0.887	0.713	.019	16	view →
CCRCC	DFS	Tertile	IV	0.887	0.260	.024	6	view →
LUAD	OS	Median	III,IV	0.808	0.299	.026	4	view →
PDAC	OS	Tertile	IV	0.934	0.231	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

TRNT1–UCEC (DFS)

Open the UCEC breakdown →