TRNT1

Across TCGA patient cohorts, TRNT1 mutation is significantly associated with the RNA expression of many other genes, with 837 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRNT1-associated genes across cancer lineages are RNA5SP411, RNA5SP412, and MIR8073. Each is linked with TRNT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRNT1-to-partner and partner-to-TRNT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP411 grouped by TRNT1-low versus TRNT1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRNT1→partner) and Y-score (partner→TRNT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP411 →	+0.954	+2.071	.001	.003	3	2
UCEC	RNA5SP412 →	+0.443	+2.315	.005	.002	3	2
BLCA	MIR8073 →	+0.693	+5.018	<.001	.004	3	2
SKCM	OR5AM1P →	+0.061	+6.797	<.001	<.001	3	2
BRCA	DEFB103A →	+0.059	+8.055	<.001	.007	3	1
BRCA	RNU6-543P →	+0.283	+8.055	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 837 associations by consensus.

RNA5SP411 by TRNT1 expression — UCEC

Explore this box plot interactively →