TRMT61A

Across TCGA patient cohorts, TRMT61A mutation is significantly associated with the RNA expression of many other genes, with 298 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRMT61A-associated genes across cancer lineages are SLC25A4, TGM7, and TENT2. Each is linked with TRMT61A in more than 1 cancer types. Because this analysis shows association rather than direction, both TRMT61A-to-partner and partner-to-TRMT61A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC25A4 grouped by TRMT61A-low versus TRMT61A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMT61A→partner) and Y-score (partner→TRMT61A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SLC25A4 →	+0.659	+3.332	.004	.005	3	1
UCEC	TGM7 →	+1.120	+3.217	.007	.009	3	1
UCEC	TENT2 →	+0.606	+3.332	.004	.005	3	1
UCEC	NUDT2 →	+0.845	+3.202	<.001	.009	3	1
UCEC	ARF4 →	+0.708	+3.343	.004	.005	3	1
UCEC	FEN1 →	+0.793	+3.354	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 298 associations by consensus.

SLC25A4 by TRMT61A expression — UCEC

Explore this box plot interactively →