TRMT61A

Across TCGA cell cohorts, TRMT61A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,413 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TRMT61A-associated GO terms across cancer lineages are Ribosomal small subunit biogenesis, Ribosome biogenesis, and Maturation of SSU-rRNA. Each is linked with TRMT61A in more than 18 cancer types. Because this analysis shows association rather than direction, both TRMT61A-to-partner and partner-to-TRMT61A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal small subunit biogenesis grouped by TRMT61A-low versus TRMT61A-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMT61A→partner) and Y-score (partner→TRMT61A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Ribosomal small subunit biogenesis →	+0.101	+0.775	.002	.007	3	19
BLOOD_Lymphoma	Ribosome biogenesis →	+0.096	+1.062	<.001	<.001	3	18
URINARY_TRACT	Maturation of SSU-rRNA →	+0.115	+1.039	<.001	<.001	3	17
LIVER	rRNA metabolic process →	+0.107	+0.809	<.001	.001	3	16
LIVER	rRNA processing →	+0.119	+0.815	<.001	<.001	3	16
BONE	rRNA transcription →	+0.123	+0.814	.001	.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,413 associations by consensus.

Ribosomal small subunit biogenesis by TRMT61A expression — LIVER

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