TRMT6

Across TCGA cell cohorts, TRMT6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,424 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TRMT6-associated GO terms across cancer lineages are DNA-templated transcription termination, DNA strand elongation, and Transcription by RNA polymerase I. Each is linked with TRMT6 in more than 15 cancer types. Because this analysis shows association rather than direction, both TRMT6-to-partner and partner-to-TRMT6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription termination grouped by TRMT6-low versus TRMT6-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMT6→partner) and Y-score (partner→TRMT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA-templated transcription termination →	+0.108	+0.766	<.001	.002	3	16
PANCREAS	DNA strand elongation →	+0.132	+0.791	<.001	.002	3	14
BONE	Transcription by RNA polymerase I →	+0.107	+0.783	<.001	<.001	3	14
BONE	DNA strand elongation involved in DNA replication →	+0.152	+0.665	.008	.004	2	14
CNS	Nuclear division →	+0.094	+0.788	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Regulation of mitochondrial mRNA stability →	+0.103	+0.639	.001	.009	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,424 associations by consensus.

DNA-templated transcription termination by TRMT6 expression — BONE

Explore this box plot interactively →