TRMT5

Across TCGA patient cohorts, TRMT5 mutation is significantly associated with the RNA expression of many other genes, with 2,515 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRMT5-associated genes across cancer lineages are MIR6803, RNA5SP411, and RNU6-128P. Each is linked with TRMT5 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRMT5-to-partner and partner-to-TRMT5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6803 grouped by TRMT5-low versus TRMT5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMT5→partner) and Y-score (partner→TRMT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6803 →	+0.114	+4.019	<.001	.005	3	3
UCEC	RNA5SP411 →	+1.233	+2.152	<.001	<.001	3	2
CESC	RNU6-128P →	+0.391	+5.306	<.001	.006	3	2
BLCA	MIR4714 →	+0.535	+3.130	<.001	.007	3	2
COAD	LAMTOR3P1 →	+0.343	+3.861	<.001	.002	3	2
COAD	RPL10P11 →	+0.250	+3.338	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,515 associations by consensus.

MIR6803 by TRMT5 expression — UCEC

Explore this box plot interactively →