TRMT2B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRMT2B mutation is significantly associated with the RNA expression of many other genes, with 2,883 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRMT2B-associated genes across cancer lineages are RNA5SP423, RN7SL22P, and ABHD17AP8. Each is linked with TRMT2B in more than 1 cancer types. Because this analysis shows association rather than direction, both TRMT2B-to-partner and partner-to-TRMT2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMT2B→partner) and Y-score (partner→TRMT2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRNA5SP423 →+0.358+5.252<.001.00232
BRCARN7SL22P →+0.251+4.733<.001.00132
HNSCABHD17AP8 →+0.290+5.303<.001.00632
SKCMMIR4772 →+0.636+5.292<.001<.00132
SKCMMIR5192 →+0.489+3.501<.001.00532
SKCMDPRXP7 →+0.063+4.993<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,883 associations by consensus.

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