TRMT1L

Across TCGA cell cohorts, TRMT1L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,017 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRMT1L-associated GO terms across cancer lineages are Protein localization to nucleus, R-loop processing, and snRNA metabolic process. Each is linked with TRMT1L in more than 11 cancer types. Because this analysis shows association rather than direction, both TRMT1L-to-partner and partner-to-TRMT1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to nucleus grouped by TRMT1L-low versus TRMT1L-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMT1L→partner) and Y-score (partner→TRMT1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Protein localization to nucleus →	+0.057	+0.813	.004	.006	3	12
LUNG_NSCLC_LUSC	R-loop processing →	+0.111	+0.668	<.001	.002	3	12
LARGE_INTESTINE	snRNA metabolic process →	+0.042	+0.439	.008	.004	3	12
LARGE_INTESTINE	snRNA processing →	+0.061	+0.503	.002	.003	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of cell cycle G2/M phase transition →	+0.062	+0.617	<.001	<.001	3	11
LIVER	Protein localization to cilium →	+0.084	+0.862	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,017 associations by consensus.

Protein localization to nucleus by TRMT1L expression — BLOOD_Myeloma

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