Across TCGA patient cohorts, TRMT12 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRMT12-associated genes across cancer lineages are ATM, PDCD4, and INPP4B. Each is linked with TRMT12 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRMT12-to-partner and partner-to-TRMT12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMT12→partner) and Y-score (partner→TRMT12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ATM →	-0.715	-2.991	<.001	.036	3	3
UCEC	PDCD4 →	-0.689	-2.736	<.001	<.001	3	2
UCEC	INPP4B →	-0.274	-3.459	.021	.005	3	2
COAD	Notch1 →	+0.257	+3.008	.007	.019	2	2
COAD	TSC1 →	-0.536	-3.000	<.001	.034	3	1
UCEC	EGFR_pY1068 →	-0.196	-1.847	.033	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Exploration

TRMT12 survival (RNA) · tumor vs normal (RNA) · all TRMT12 data types