Across TCGA pan-cancer cohorts, TRMT112 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated TRMT112 data layer compared with 25 for mass-spec protein and 6 for mass-spec protein.
The strongest signal is observed in breast invasive carcinoma (BRCA), where higher TRMT112 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRMT112 expression acts as an unfavorable survival marker.
BRCA are the cancer types where TRMT112 Mutation most reproducibly stratifies survival.