TRMT112

Across TCGA patient cohorts, TRMT112 protein abundance is significantly associated with the RNA expression of many other genes, with 8,828 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TRMT112-associated genes across cancer lineages are ELL2, HEATR1, and FAM86C2P. Each is linked with TRMT112 in more than 3 cancer types. Because this analysis shows association rather than direction, both TRMT112-to-partner and partner-to-TRMT112 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRMT112 versus ELL2 in GBM, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMT112→partner) and Y-score (partner→TRMT112) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ELL2 →	-0.865	-0.200	<.001	<.001	3	4
LSCC	HEATR1 →	+0.496	+0.210	.003	.001	3	4
LSCC	FAM86C2P →	+0.588	+0.248	<.001	<.001	3	4
LSCC	PMS2P1 →	+0.566	+0.297	<.001	<.001	3	4
LSCC	MALSU1 →	+0.306	+0.154	.006	.005	3	4
PDAC	AMY2B →	-1.881	-0.543	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,828 associations by consensus.

TRMT112 vs ELL2 — GBM

Explore this scatter interactively →