TRMT112

Across TCGA cell cohorts, TRMT112 mutation is significantly associated with the mutation status of many other genes, with 597 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRMT112-associated genes across cancer lineages are ZNF773, TEKT5, and SMARCA5. Each is linked with TRMT112 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRMT112-to-partner and partner-to-TRMT112 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF773 grouped by TRMT112-low versus TRMT112-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMT112→partner) and Y-score (partner→TRMT112) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ZNF773 →	+6.321	+6.321	.001	.001	1	1
BLOOD_Leukemia	TEKT5 →	+4.000	+5.050	.008	.008	1	1
BLOOD_Leukemia	SMARCA5 →	+4.321	+5.285	.005	.005	1	1
BLOOD_Leukemia	UBP1 →	+6.321	+6.321	.001	.001	1	1
BLOOD_Leukemia	JPH3 →	+4.000	+5.050	.008	.008	1	1
BLOOD_Leukemia	UBASH3B →	+4.321	+5.285	.005	.005	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 597 associations by consensus.

ZNF773 by TRMT112 expression — BLOOD_Leukemia

Explore this box plot interactively →