TRMT10C

Across TCGA pan-cancer cohorts, TRMT10C mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TRMT10C data layer compared with 18 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TRMT10C mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TRMT10C expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

LUAD, LSCC, and COAD are the cancer types where TRMT10C mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	III,IV	0.687	0.281	.012	17	view →
LSCC	DFS	Tertile	II,III,IV	1.000	0.826	.020	7	view →
COAD	DFS	Median	IV	0.493	0.944	.031	6	view →
UCEC	DFS	Median	All	0.765	0.947	.003	6	view →
GBM	DFS	Quartile	All	0.231	0.467	.035	5	view →
HNSC	DFS	Median	III,IV	0.747	0.487	.017	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

TRMT10C–LUAD (DFS)

Open the LUAD breakdown →