TRMT10A

Across TCGA cell cohorts, TRMT10A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,263 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TRMT10A-associated GO terms across cancer lineages are tRNA methylation, Box C/D sno(s)RNA metabolic process, and Box C/D sno(s)RNA processing. Each is linked with TRMT10A in more than 16 cancer types. Because this analysis shows association rather than direction, both TRMT10A-to-partner and partner-to-TRMT10A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA methylation grouped by TRMT10A-low versus TRMT10A-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMT10A→partner) and Y-score (partner→TRMT10A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	tRNA methylation →	+0.056	+0.697	<.001	<.001	3	17
BLOOD_Myeloma	Box C/D sno(s)RNA metabolic process →	+0.109	+1.170	.003	.001	3	14
BLOOD_Myeloma	Box C/D sno(s)RNA processing →	+0.109	+1.170	.003	.001	3	14
BLOOD_Myeloma	Box C/D sno(s)RNA 3'-end processing →	+0.109	+1.170	.003	.001	3	14
SKIN	tRNA N1-guanine methylation →	+0.459	+0.827	.008	<.001	2	14
OVARY	tRNA modification →	+0.045	+0.684	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,263 associations by consensus.

tRNA methylation by TRMT10A expression — OVARY

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