TRMT1

Across TCGA cell cohorts, TRMT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,029 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TRMT1-associated GO terms across cancer lineages are IMP biosynthetic process, rRNA metabolic process, and Transcription initiation at RNA polymerase I promoter. Each is linked with TRMT1 in more than 17 cancer types. Because this analysis shows association rather than direction, both TRMT1-to-partner and partner-to-TRMT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IMP biosynthetic process grouped by TRMT1-low versus TRMT1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMT1→partner) and Y-score (partner→TRMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	IMP biosynthetic process →	+0.212	+0.915	<.001	<.001	3	18
CNS	rRNA metabolic process →	+0.099	+0.764	<.001	<.001	3	17
PANCREAS	Transcription initiation at RNA polymerase I promoter →	+0.122	+0.849	<.001	<.001	3	17
BONE	Ribosome biogenesis →	+0.098	+0.614	<.001	<.001	3	16
BONE	Maturation of LSU-rRNA →	+0.178	+0.938	<.001	<.001	3	16
BONE	rRNA processing →	+0.151	+0.998	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,029 associations by consensus.

IMP biosynthetic process by TRMT1 expression — URINARY_TRACT

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