TRIT1

Across TCGA cell cohorts, TRIT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,850 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRIT1-associated GO terms across cancer lineages are Regulation of centrosome duplication, snRNA metabolic process, and Microtubule organizing center organization. Each is linked with TRIT1 in more than 15 cancer types. Because this analysis shows association rather than direction, both TRIT1-to-partner and partner-to-TRIT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of centrosome duplication grouped by TRIT1-low versus TRIT1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIT1→partner) and Y-score (partner→TRIT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of centrosome duplication →	+0.113	+1.181	<.001	<.001	3	16
STOMACH	snRNA metabolic process →	+0.059	+0.782	.001	.003	3	13
BONE	Microtubule organizing center organization →	+0.080	+0.895	.005	.006	3	13
LARGE_INTESTINE	Nuclear pore organization →	+0.093	+0.519	<.001	.001	3	13
STOMACH	Sister chromatid cohesion →	+0.090	+0.557	<.001	.001	3	13
SOFT_TISSUE	Centrosome cycle →	+0.084	+0.679	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,850 associations by consensus.

Regulation of centrosome duplication by TRIT1 expression — BONE

Explore this box plot interactively →