TRIT1

Across TCGA cell cohorts, TRIT1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRIT1-associated genes across cancer lineages are LACRT and DMRTC2. Each is linked with TRIT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIT1-to-partner and partner-to-TRIT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LACRT grouped by TRIT1-low versus TRIT1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIT1→partner) and Y-score (partner→TRIT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	LACRT →	+0.230	+4.981	<.001	.008	3	1
BLOOD_Leukemia	DMRTC2 →	+0.036	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

LACRT by TRIT1 expression — CNS

Explore this box plot interactively →