Across TCGA pan-cancer cohorts, TRIQK RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated TRIQK data layer compared with 1 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher TRIQK RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated TRIQK expression acts as an unfavorable survival marker, although some lineages such as KIRC and MESO show a favorable association.

KIRC, MESO, and LUSC are the cancer types where TRIQK RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.705	0.542	<.001	80	view →
MESO	OS	Median	All	0.497	0.277	<.001	55	view →
LUSC	DFS	Quartile	III,IV	0.386	0.742	.002	42	view →
UVM	DFS	Quartile	III,IV	0.289	0.835	.003	35	view →
KIRP	DFS	Median	All	0.797	0.934	.003	26	view →
STAD	OS	Median	II,III,IV	0.453	0.656	.019	23	view →
SARC	OS	Tertile	All	0.680	0.825	.007	22	view →
SKCM	DFS	Median	IV	0.067	0.732	.001	21	view →
HNSC	OS	Tertile	All	0.609	0.824	.013	19	view →
CESC	DFS	Quartile	All	0.637	0.810	.010	16	view →
SCLC	OS	Median	All	0.505	0.921	.010	13	view →
CHOL	OS	Median	All	0.721	0.433	.018	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

Exploration

Same gene, other analysis: TRIQK tumor-vs-normal RNA expression · all TRIQK data types