TRIP4

Across TCGA patient cohorts, TRIP4 protein abundance is significantly associated with the RNA expression of many other genes, with 12,202 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TRIP4-associated genes across cancer lineages are ASCC3, GTF3C6, and EPHX1. Each is linked with TRIP4 in more than 7 cancer types. Because this analysis shows association rather than direction, both TRIP4-to-partner and partner-to-TRIP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIP4 versus ASCC3 in BRCA, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIP4→partner) and Y-score (partner→TRIP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ASCC3 →	+0.566	+0.162	<.001	.004	3	8
LSCC	GTF3C6 →	+0.604	+0.196	<.001	<.001	3	6
HNSC	EPHX1 →	-1.296	-0.271	<.001	<.001	3	5
BRCA	TMEM8B →	-0.680	-0.237	<.001	<.001	3	5
OV	MORN4 →	-0.865	-0.240	<.001	.001	3	5
BRCA	DACH1 →	-1.968	-0.215	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,202 associations by consensus.

TRIP4 vs ASCC3 — BRCA

Explore this scatter interactively →