TRIP4

Across TCGA patient cohorts, TRIP4 mutation is significantly associated with the RNA expression of many other genes, with 1,086 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIP4-associated genes across cancer lineages are SNORD116-16, RN7SL62P, and RNA5SP73. Each is linked with TRIP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIP4-to-partner and partner-to-TRIP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD116-16 grouped by TRIP4-low versus TRIP4-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIP4→partner) and Y-score (partner→TRIP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SNORD116-16 →	+0.625	+2.915	<.001	.002	3	2
CESC	RN7SL62P →	+0.110	+4.812	<.001	.006	3	2
CESC	RNA5SP73 →	+0.332	+5.837	<.001	.001	3	2
CESC	CFAP97P1 →	+0.201	+4.364	<.001	.006	3	2
CESC	LINC01202 →	+0.293	+4.539	<.001	.008	3	2
UCEC	PHF5A →	+0.481	+3.595	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,086 associations by consensus.

SNORD116-16 by TRIP4 expression — SKCM

Explore this box plot interactively →