TRIP13

Across TCGA patient cohorts, TRIP13 protein abundance is significantly associated with the RNA expression of many other genes, with 17,368 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TRIP13-associated genes across cancer lineages are CENPI, TTK, and CENPA. Each is linked with TRIP13 in more than 9 cancer types. Because this analysis shows association rather than direction, both TRIP13-to-partner and partner-to-TRIP13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIP13 versus CENPI in LUAD, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIP13→partner) and Y-score (partner→TRIP13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CENPI →	+1.174	+0.960	<.001	<.001	3	10
UCEC	TTK →	+1.350	+0.767	<.001	<.001	3	10
OV	CENPA →	+1.401	+0.761	<.001	<.001	3	10
LUAD	CDC20 →	+1.662	+1.079	<.001	<.001	3	10
LUAD	NEK2 →	+1.372	+0.957	<.001	<.001	3	10
LUAD	CENPF →	+1.343	+0.892	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,368 associations by consensus.

TRIP13 vs CENPI — LUAD

Explore this scatter interactively →