TRIP11

Across TCGA cell cohorts, TRIP11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,261 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TRIP11-associated GO terms across cancer lineages are Vesicle tethering to Golgi, Vesicle tethering, and Monoubiquitinated protein deubiquitination. Each is linked with TRIP11 in more than 18 cancer types. Because this analysis shows association rather than direction, both TRIP11-to-partner and partner-to-TRIP11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle tethering to Golgi grouped by TRIP11-low versus TRIP11-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIP11→partner) and Y-score (partner→TRIP11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Vesicle tethering to Golgi →	+0.114	+0.725	<.001	<.001	3	19
OESOPHAGUS	Vesicle tethering →	+0.095	+0.778	.002	<.001	3	18
OVARY	Monoubiquitinated protein deubiquitination →	+0.127	+0.845	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.062	+0.768	.005	.002	3	17
LARGE_INTESTINE	Golgi organization →	+0.061	+0.819	<.001	<.001	3	16
PANCREAS	miRNA processing →	+0.081	+0.547	.001	.005	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,261 associations by consensus.

Vesicle tethering to Golgi by TRIP11 expression — OESOPHAGUS

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