TRIP10

Across TCGA patient cohorts, TRIP10 protein abundance is significantly associated with the RNA expression of many other genes, with 15,347 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRIP10-associated genes across cancer lineages are HRH1, SYDE1, and CAV2. Each is linked with TRIP10 in more than 6 cancer types. Because this analysis shows association rather than direction, both TRIP10-to-partner and partner-to-TRIP10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIP10 versus HRH1 in OV, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIP10→partner) and Y-score (partner→TRIP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HRH1 →	+1.259	+0.428	<.001	<.001	3	7
OV	SYDE1 →	+1.091	+0.357	<.001	.001	3	7
BRCA	CAV2 →	+1.114	+0.308	<.001	<.001	3	6
GBM	CAV1 →	+1.470	+0.465	<.001	<.001	3	6
OV	SH2D3A →	+1.205	+0.540	<.001	<.001	3	6
LSCC	RRAS →	+0.708	+0.254	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,347 associations by consensus.

TRIP10 vs HRH1 — OV

Explore this scatter interactively →